Molecular Endocrinology and Physiology of the Aging Central Nervous System

Molecular endocrinology and physiology of the aging central nervous system.

Aging is associated with a progressive decline in physical and cognitive functions. The impact of age-dependent endocrine changes regulated by the central nervous system on the dynamics of neuronal behavior, neurodegeneration, cognition, biological rhythms, sexual behavior, and metabolism are reviewed. We also briefly review how functional deficits associated with increases in glucocorticoids a...

Molecular physiology of P2 receptors in the central nervous system.

Neurons of the central nervous system (CNS) are endowed with ATP-sensitive receptors belonging to the P2X (ligand-gated cationic channels) and P2Y (G protein-coupled receptors) types. Whereas a number of P2X receptors mediate fast synaptic responses to the transmitter ATP, P2Y receptors mediate either slow changes of the membrane potential in response to non-synaptically released ATP or the int...

ADENOSINE IN THE CENTRAL NERVOUS SYSTEM

Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...

Physiology of the Central Nervous System and Special Senses

Physiology of the Central Nervous System and Special Senses

L.M. &s, Grant Medical College, Bombay. Uud Edition. Messrs, James & Sons, Bombay, 1912. This author in publishing this compilation in a second edition has carefully revised and enlarged his work. It provides the senior student with a brief resume of a fair amount of the knowledge that would be expected from him by an examiner, otherwise the volume cannot be considered of much real value. Read ...